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2012-3-9 16:13 上传
Here, we have the heart. We’ve been speaking about the heart because we’re talking about the cardiovascular system or the circulatory system and the heart has a very important job. It’s pumping the blood throughout the body. The blood carries oxygen and nutrients to the muscles and to the other organs that need this in order for you to live; in order for you to do all the things that you are doing right now.
We’re going away from the heart via the aorta and then, we go to the arteries. We’re going away — a very easy way of remembering this is the ‘a’ in ‘arteries,’ ‘arterioles,’ and ‘aorta’ is going ‘away’ from the heart. When it reaches the tissues and the organs, it’s going to have an exchange in the capillaries where it then goes into the venules, to the veins, and then, back via the vena cava to the heart.
Let’s look at pressure on the y-axis. I’m going to give these some values of 20 (let me just write them in here first. Okay, it’s not fully evenly spaced), 20, 40, 60, 80, 100, 120, and 140. On the y-axis we’re dealing (I’m just going to write it over here), with pressure in millimeters of Mercury (mm Hg).
When the heart contracts, we have ventricular contraction and that’s when we’re going to get the greatest amount of pressure because the ventricles are larger than the atria. When they contract sending the blood to the rest of the body, that’s going to give you the systolic pressure, which is going to be the greatest pressure. We’re going to see here, (let me draw this in… Let’s go with red), the ventricles are contracting so the pressure is going to increase significantly and then, as the atria contract, you’re going to get that little bump there. That process continues as the heart beats, continues as the heart beats. We’re in the arteries.
As we go away from the arteries and into the arterioles, what you’re going to see, we’re getting away from the heart a little bit, the pressure is going to start kind of going down, going down. As you go away, you’re going to see smaller fluctuations. You’re not getting as great of an effect. As we reach into the capillaries, it’s kind of dying down even more and the pressure is going to continue going down and down until, on the way back to the heart, there’s hardly any pressure remaining. I mean, in comparison to up here, where we had pressures of up to 120 mm Hg, or sometimes even more in this situation, in comparison, the farther away we get from the heart and as the blood is being pushed back to the heart, we don’t get these fluctuations in pressure and there’s significantly less pressure as the blood is going back to the heart.
When the doctor takes your pressure and the doctor says, “You are in excellent health. Your blood pressure is great,” what are the numbers that you usually hear? The numbers that you usually hear are 120 over 80 (120/80). What that refers to, of course at the top, we have the systolic pressure and here we have the diastolic pressure – systolic pressure and diastolic pressure. Systolic is during systole contraction so, that’s the higher point. Diastolic is during relaxation where we have a lower point. If you have that 120/80, you are a happy camper. All is well with the world, at least where your blood pressure is concerned. That is what we want to have.
That is blood pressure. When you’re measuring blood pressure, you’re measuring the difference between systole and diastole – contraction and relaxation.
Now, let’s talk a little bit about ‘mean arterial pressure.’ (I’m just going to write M.A.P. for short). Mean arterial pressure, when you hear the word ‘mean,’ you always think average. The mean arterial pressure is basically the average pressure in the arteries. We’re not looking at the fluctuations. We are looking at the average. If we were to take the average here, I’m just going to plot a second line, it would look something like this. So, straight line here and as it goes down, it’s going to look a little like this until where we have a straight line here, it follows that straight line. That gives us the average pressure in the arteries.
There’s a formula that we use to calculate mean arterial pressure. Mean arterial pressure, M.A.P., is going to be equal to CO times PR.
M.A.P. = CO x PR
Now, two of these you know already: M.A.P., mean arterial pressure; and CO, you should know that that is cardiac output. PR is one that we haven’t covered. PR is ‘peripheral resistance.’ As I said,
M.A.P. = CO x PR
M.A.P. = diastolic BP + 1/3 (systolic BP – diastolic BP)
M.A.P. = 80 + 1/3 (40) = 80 + 13 = 93
M.A.P. = 80 + 1/3 (40) = 80 + 13 = 93 mm Hg
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