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地塞米松预防术后寒战的报道早在1998年就有了【1】,之后也有很多进一步的研究证实其这方面的作用【2,3】。机制可能与地塞米松降低了核心体温和皮肤温度之间的梯度,并且抑制了炎症反应有关。
附参考文献:
1、Yared JP, Starr NJ, Hoffmann-Hogg L, et al. Dexamethasone decreases the incidence of shivering after cardiac surgery: a randomized, double-blind, placebo-controlled study. Anesth Analg. 1998;87(4):795-9.
2、Song YK, Lee C. Effects of ramosetron and dexamethasone on postoperative nausea, vomiting, pain, and shivering in female patients undergoing thyroid surgery. J Anesth. 2013;27(1):29-34。
3、Entezariasl M, Isazadehfar K. Dexamethasone for prevention of postoperative shivering: a randomized double-blind comparison with pethidine. Int J Prev Med. 2013;4(7):818-24. |
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