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发表于 2019-3-4 21:58:05
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建议采用侧卧位行椎管内麻醉的研究
本帖最后由 maximolin 于 2019-3-4 21:59 编辑
Literature search identified 7 eligible RCTs (6 on spinal anesthesia and only one on neurologic diagnosis) with 1,101patients, of which 557 hadlumbarpunctures in lateral decubituspositionand 544 insittingposition. Only 3 (out of 7) RCTs favored the lateral decubituspositionto significantly reduce the PDPH. Meta-analysis showed that the lateral decubituspositionwas associated with a significant reduction of the incidence of PDPH (risk ratio [RR] = 0.61, 95% confidence interval [CI] = 0.44-0.86, P = 0.004, I2 = 25%, P for heterogeneity = 0.24) compared with thesittingposition. Subgroup analysis showed that lateral decubituspositionis also associated with reduction of PDPH in spinal anesthesia (RR = 0.69, 95% CI = 0.50-0.95, I2 = 0%, P for heterogeneity = 0.42). We found no statistically significant association between lateral decubituspositionandsuccessfulplacement of spinal needle at first attempt (RR = 1.00, 95% CI = 0.92-1.09, P = 0.94, I2 = 73%, P for heterogeneity = 0.01). There was no evidence of publication bias in our analyses (Egger's bias = -0.05, P = 0.96).
文献检索确定了7个符合条件的随机对照试验(6个关于脊髓麻醉,只有一个关于神经系统诊断),1101名患者,其中557名患者在侧卧位行腰椎穿刺,544名患者在坐位行腰椎穿刺。只有3个(7个)随机对照试验支持侧卧位显著降低PDPH。荟萃分析显示,与坐位相比,侧卧位与PDPH发生率显著降低相关(风险比[RR]=0.61,95%置信区间[CI]=0.44-0.86,P=0.004,I2=25%,异质性P=0.24)。亚组分析表明,侧卧位也与脊髓麻醉时PDPH的降低有关(RR=0.69,95%CI=0.50-0.95,I2=0%,异质性P=0.42)。我们发现侧卧位与首次成功放置脊髓针之间没有统计学意义上的相关性(RR=1.00,95%CI=0.92-1.09,P=0.94,I2=73%,异质性P=0.01)。在我们的分析中没有发表偏见的证据(爱格的偏见为-0.05,p=0.96)。
Zorrillavaca A , Makkar J K . Effectiveness of Lateral Decubitus Position for Preventing Post-Dural Puncture Headache: A Meta-Analysis.[J]. Pain Physician, 2017, 20(4):E521.
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