大麻使用障碍和择期手术围手术期手术的结果：回顾性队列分析

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Cannabis Use Disorder and Perioperative Outcomes in Major Elective Surgeries: A Retrospective Cohort Analysis

                    大麻使用障碍与择期手术围手术期手术的结果：回顾性队列分析

Surgical patients with an active cannabis use disorder may be at an increased risk of adverse outcomes given the potential for psychoactive and hemodynamic effects within the perioperative setting.

有持续性大麻使用障碍的外科患者因为在围手术期可能会产生精神和血流动力学效应而产生不良后果的风险。

A retrospective cohort study was conducted to test the hypothesis that nonambulatory surgery patients with an active cannabis use disorder have a higher risk of postoperative complications using data obtained from the Nationwide Inpatient Sample from 2006 to 2015.

从2006年至2015年获得的全国住院样本中进行了一项回顾性队列研究，以检验非卧床手术患者有活动性大麻使用障碍术后并发症更高风险的假设  。

The primary composite outcome consisted of clinically relevant postoperative complications, including myocardial infarction, stroke, sepsis, deep vein thrombosis/pulmonary embolus, acute kidney injury requiring dialysis, respiratory failure, and in-hospital mortality.

主要综合结果包括临床相关的术后并发症，包括心肌梗死、中风、脓毒症、深静脉血栓形成/肺栓塞、急性肾损伤 需要透析、呼吸衰竭和住院死亡率。

A propensity score matched-pairs analysis of the cohort was used to evaluate the adjusted association between active cannabis use disorders and the outcome of interest; the matched-pairs cohort consisted of 13,603 patients in each group.

使用倾向性得分配对分析来评估活跃的大麻使用障碍与临床结果之间关联；配对队列每组13603例。

There was no statistically significant difference in the composite perioperative outcome between patients with (400 of 13,603; 2.9%) and without (415 of 13,603; 3.1%) a reported active cannabis use disorder (adjusted odds ratio 0.97; 95% CI, 0.84 to 1.11). See the accompanying Editorial on page 612. (Summary: M. J. Avram. Image: Adobe Stock.)

报告的大麻使用活跃的患者（13,603例中有400例；2.9%)和未报告的(13,603例中有415例；3.1%）的综合围手术期结果无统计学差异 等序(调整优势比0.97；95%CI，0.84至1.11)。