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When local infiltration anesthetia using anesthetics containing adrenaline is applied on area with abundant bloodstream in the surgeries of otolaryngology, stomatology, neurosurgery, cosmetic surgery et al., hemodynamic values change significantly according to the blood level of quick absorbed adrenaline. The clinical commonly used dose of adrenaline usually causes the decrease of systemic vascular resistance and blood pressure, and the increase of myocardial contractility and heart rate under relative deep general anesthesia. The clinical commonly used concentration of adrenaline may reduce bleeding on operating field, and further raising the concentration of adrenaline doesn’t enhance hemostasis and would induce more dramatic and complicated hemodynamic changes.
在耳鼻喉科、神经外科、口腔科、头颈外科以及整形科等手术过程中,由于手术及局部浸润麻醉部位血流丰富,在注射含肾上腺素的局部麻醉药时,机体会快速吸收肾上腺素并引起一系列血流动力学变化;血流动力学变化情况与肾上腺素的用量有关;在较深的全身麻醉下,临床上常用剂量的肾上腺素通常引起以外周血管阻力下降、血压下降、心肌收缩力增强和心率增快为主的血流动力学变化过程;临床上常用浓度的肾上腺素可以明显的减少手术野出血,进一步提高肾上腺素的浓度不能提高止血效果,却会引起更大更复杂的血流动力学变化 |
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