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fanhui 发表于 2013-8-13 18:43:42

咪唑安定具有苯二氮卓类所共有的抗焦虑、催眠、抗惊厥、肌松和顺行性遗忘等作用，由于其消除半衰期短（0.7小时）和清除率高（100ml/min）故其可控性,目前已广泛用于临床。靶控输注是以药代动力学药效学为基础，通过调节目标药物浓度来控制麻醉深度的方法，临床应用可显示预期血药浓度。已证实咪唑安定靶控输注用于镇静时血药浓度与脑电双频指数（BIS）评分的相关性好｛1｝。腰+硬麻醉下用咪唑安定给以预定血药浓度观察BIS值判定患者镇静程度，从而判定辅助用药的临床效果。
Midazolam with benzene two nitrogen Zhuo class common anxiolytic, hypnotic, anticonvulsant, muscle relaxant and anterograde amnesia effect, because it has a short elimination half-life (0.7 h) and clearance rate (100ml/min) so the controllability, has been widely used in clinical. Target controlled infusion with pharmacokinetic pharmacodynamic basis, to control the depth of anesthesia by adjusting the target drug concentration, clinical application can display the target plasma concentration. Has confirmed the target controlled infusion of midazolam for sedation of serum drug concentration and bispectral index (BIS) score correlated well {1}. Give a predetermined plasma concentrations observed BIS values to determine the degree of sedation with midazolam waist + epidural anesthesia, to determine the clinical effect of adjuvant.

蚂蚁未成熟 发表于 2013-8-14 16:44:57

A myofascial trigger point is a hyperirritable point in skeletal muscle that is associated with a hypersensitive palpable nodule.肌筋膜扳机点是一个在骨骼肌上过度应激的点，与高度敏感可以触及的硬结有关。
Travell JG, Simons DG. Myofascial pain and dysfunction: the trigger point manual. Baltimore
(MD): Williams and Wilkins; 1983.

xyyx618 发表于 2013-8-14 18:18:25

Anesthesia and elective operations should not proceed until the patient is in optimal medical condition。
择期手术与麻醉需要在患者达到最佳身体状况下，才能实施麻醉。
《摩根临床麻醉学》4th第一章 P1

tianxing447 发表于 2013-8-15 12:46:54

小心驶的万年船
Caution is the parent of safety

fangwan1981 发表于 2013-8-15 20:51:12

all thingscometothosewhowait.
苍天不负有心人

宜春妹子 发表于 2013-8-15 22:12:56

Very often a change of self is needes more than a change of scene.很多时候你更需要的是改变自己,而不是换个环境.

yinyilei 发表于 2013-8-16 18:34:27

回复 15# shenxiu2
这句话使用有道词典翻译是：麻醉药物往往是高度绑定到蛋白质在等离子体和高度绑定到脂质在外围组织
我也不太清楚对不。:P

anyi189 发表于 2013-8-17 01:27:41

MAC值越小,则麻醉药的效能越强

MAC smaller the value, the stronger the performance of anesthetic

出自 米勒麻醉学

bhltbyy 发表于 2013-8-18 01:07:57

At least half of these events could have been prevented and may have resulted from deviations from accepted anesthesia practices
至少半数的不良反应是可以预防的，而且这些问题是由麻醉操作的差错所致

clinical Anesthesia Procedures of the Massachusetts General Hospital

whl87 发表于 2013-8-18 11:30:22

Descending systems contributing to
locomotor recovery after mild or moderate
spinal cord injury in rats: experimental
evidence and a review of literature
下行系统在大鼠脊髓轻中度损伤运动功能恢复中起的作用：实验证据和回顾调查
Restorative Neurology and Neuroscience 20 (2002) 189–218 189
IOS Press

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