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Introduction
During surgery in infants, as in all patients, it is desir-able to avoid both inadequate and excessive doses of
anesthesia. Inadequate doses result in intra-operative
distress, whereas excessive doses may cause cardiore-spiratory depression. In the past decade, evidence has
accumulated of neuronal apoptotic effects of anesthe-sia on the developing brains of animals (1,2). To date,
there are no comparable data in humans (3), but if, in
the future, minimisation of anesthesia dose is consid-ered important, a monitor of anesthesia depth may
become valuable in infants. Processed electroencepha-lography (EEG) and other monitors of conscious level
have been developed in adults but are not reliably
applied to infants because the infant EEG is different.
Because young infants do not communicate, any moni-tor developed for infants will need to be tested against
a validated scale or descriptive tool of behavior related
to consciousness.
前言
婴儿和其他所有患者一样,在手术过程中,需要避免麻醉药剂量的不足和过量。麻醉药剂量不足会导致手术中的疼痛,而麻醉药过量可能导致心脏和呼吸的抑制。在过去的10年间,已经有证据表明,麻醉对于正在发育的动物大脑可引起神经元的凋亡。迄今为止,没有在人类发现相关的数据,但是,如果在未来,认识到最低麻醉剂量的重要性,那么对于婴儿麻醉深度的监测就会很有价值。对于成年人,动态的脑电图以及其他意识水平的监测已经有了进展,但是因为婴儿的脑电图的不同,没有适用于婴儿的可靠的意识监测。由于小婴儿无法交流,任何婴儿监测的发展都需要测试与意识相关的经过验证的行为量表和描述工具。
出自:ORIGINAL ARTICLE
Defining awakening from anesthesia in infants: a narrative
review of published descriptions and scales of behavior
Michael R. J. Sury1 & Matthew D. Bould |
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