回复 20# wycfeiyu
Dexmedetomidine, like clonidine, is a potent alpha-2-adrenoceptor agonist with an 8-fold higher affinity for the alpha-2-adrenoceptor than clonidine.
如同可乐定，右美托咪啶是一种强的α2肾上腺素能受体(adrenoeeptor，α2AR)激动剂。与α2AR的亲和力是可乐定的8倍。
回复 1212# zszch
Dexmedetomidine, like clonidine, is a potent alpha-2-adrenoceptor agonist with an 8-fold higher affinity for the alpha-2-adrenoceptor than clonidine.
如同可乐定，右美托咪啶是一种强的α2肾上腺素能受体(adrenoeeptor，α2AR)激动剂。与α2AR的亲和力是可乐定的8倍。
出处：
Incidence of cardiac arrest increases with the indiscriminate use of dexmedetomidine: A case series and review of published case reports
Acta Anaesthesiologica Taiwanica 49 (2011) 165-167
The fundamental pharmacokinetic processes are dilution into volumes of distribution and clearance. These processes are governed by the physical properties of the drug and the metabolic capacity of the patient. Anesthetic drugs tend to be highly bound to protein in plasma and highly bound to lipid in peripheral tissues. Most anesthetic drugs are metabolized in the liver.
药代动力学的基本过程分为分配和清除量稀释。这些过程都受药物的物理特性和病人的代谢能力。麻醉药品往往是高度肯定的血浆蛋白和高度的约束外周组织的脂质。大多数麻醉药物在肝脏代谢。
临床及动物实验均显示，全身麻醉所需的MAC随体温的降低而减少（从42℃到26℃）。不同的全麻药在体温下降时减少用量的幅度并不相同，如体温每下降1℃，环丙烷的用量减少2%，而氟烷则减少5%。
Clinical and animal experiments have shown that, general anesthesia is required by MAC with the temperature decrease ( from 42℃ to 26℃). Different anesthetics in the temperature falls to reduce the dosage range are not the same, such as body temperature every drop of 1 ℃, cyclopropane to reduce the amount of 2%, while halothane decreased by 5%。
出自《现代麻醉学》第三版
Morgan Clinical Anesthesiology
摩根临床麻醉学
Intraoperative management
术中管理
纵隔移向健侧
Contralateral mediastinal shift
what is the reason ofthe headache after spinal anesthesia ?
脊麻后头痛原因是？
Morgan Clinical Anesthesiology No. 863
From fundamental principles to advanced subspecialty procedures, Miller's Anesthesia covers the full scope of contemporary anesthesia practice.
从基本原理到高级的附属专业规程，弥勒麻醉学囊括了全部的当代麻醉实践。
出自： Miller's Anesthesia 7Ed
Morgan Clinical Anesthesiology
摩根临床麻醉学
困难气道的定义是：具有五年以上临床麻醉经验的麻醉科医师在面罩通气时遇到了困难（上呼吸道梗阻），或气管插管时遇到了困难，或两者兼有的一种临床情况。
The definition of difficult spirit way is:Have for more than five years the clinical anaesthesia is empirical anaesthesia doctor Ke met a difficulty(up breath way block) when the mask ventilates, or the windpipe met a difficulty while putting a tube, or both and a kind of clinical circumstance for having.
Guillaume慢慢醒来，麻醉师就在他身边，他刚好带着口罩。
Guillaume est en train de se réveiller. L'anesthésiste est à côté de lui, il porte un masque